SB HLA Compass
Next-generation sequencing (NGS) for accurate HLA and MIC gene typing.
Highlights:
NGS has become the gold standard for HLA typing because it provides high-resolution, unambiguous allele identification across multiple HLA loci.
SB HLA Assay sequence 18 loci, covering HLA (classical and non-classical) and MIC genes from blood or buccal sample extracted DNA. Its exceptional design delivers consistent and reliable high-resolution results across all loci on day 2. All reagents necessary for genomic library preparation and hybrid capture enrichment are included with this high-resolution NGS genotyping assay. Support DNA from whole blood or buccal swabs across a wide input range with ready-to-use reagents.
Minimize hands-on time through single-step fragmentation, repair, and adenylation, one-step barcoding, and simplified post-capture washes. Choose between two targeted panels: one for 11 classical HLA loci and another for 7 non-classical MHC loci. Mitigate PCR amplification bias and produce consistent balanced reads using target specific capture probes. Achieve uniform, well-balanced data with hybrid capture–based targeted enrichment, while UDI indexing minimizes barcode hopping and misassignment.